Bringing you our latest discoveries in high-throughput screening, genomic and cellular analysis, colony selection, and microplate detection. Visit us at: moleculardevices.com
Lab Notes Blog Post
An automation journey for a high-throughput ELISA workflow
As a lab’s needs expand, automating every step of an intricate workflow provides exponential value. From increased walk-away time and throughput to reduced human error and improved lab safety, automation can keep routine work on track so that scientists can focus on more critical assay development challenges.
Increase Cell Painting assay throughput using an automated workstation
Cell painting workflows can be time- and labor-intensive, taking several days, and requiring screening of many assay plates. The use of automated liquid handlers, like the Biomek i7 Hybrid automated workstation can help streamline these processes, saving valuable user time and increasing assay throughput.
Read the application note to learn how to develop an automated workflow for the preparation of your Cell Painting assay plates.
CloneSelect Imager FL with flourescent imaging for rapid day zero monoclonality assurance
The CloneSelect® Imager FL (CSI-FL) offers assistance in upstream process development of cell line development workflows. The stringent regulations of cell line development monoclonality can be easily met using the fluorescence detection capabilities of CSI-FL to confirm a single cell and to provide day zero assurance of monoclonality.
In this application note, we present a fluorescent method for identifying monoclonal HEK-293 cells after gene editing with CRISPR-based p53 knockout plasmids that have a red fluorescent protein (RFP) marker for puromycin selection. The edited cells were seeded into 96-well plates with a single-cell printer. These were then monitored using CSI-FL to assess monoclonality and monitor growth through RFP and white light channels.
Stem Cell Science and Regenerative Medicine - Technology and Methods Presented at ISSCR 2022
It was another great year at ISSCR 2022! Leaders from across the globe came together to discuss new technologies, share insights, and explore the newest breakthroughs in stem cell science and regenerative medicine.
Download posters to learn about automated and quantifiable solutions for the complex 3D cell model assays:
Poster: Monitoring growth and characterization of compound effects in 3D intestinal organoids with high-content imaging
Poster: Structural Organization and Functional Analysis of Compound Response in 3D Human iPSC-derived Cardiac Tri-Culture Microtissues
Poster: Automated monitoring of development and activity analysis of iPSC-derived 3D cerebral organoids
Please be advised that this email may contain confidential information. If you are not the intended recipient, please notify us by email by replying to the sender and delete this message. The sender disclaims that the content of this email constitutes an offer to enter into, or the acceptance of, any agreement; provided that the foregoing does not invalidate the binding effect of any digital or other electronic reproduction of a manual signature that is included in any attachment.